The SAP18 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Miscellaneous, and SAP18. This antibody recognizes Human, Mouse, and Rat antigen. The SAP18 Polyclonal Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2